Droplet generation

Glass Capillaries

Double emulsion droplets with multiple inner compartments are useful as artificial cell model and controlled drug delivery vehicles.

We can control the number of inner droplets in double emulsions from 1 to 6. We can also predict the number of inner compartments by adjusting the capillary numbers of the inner, middle and outer fluids.

 

References

R. Al Nuumani, G. Bolognesi, G. and G.T. Vladisavljevic, 2018, Langmuir, 34, 11822-1183.

A.S. Nabavi, G.T. Vladisavljević, V. Manović, 2017 Chemical Engineering Journal, 322, 140

Silicon microchips with straight-through microchannels

We use silicon microchips with horizontally or vertically etched microchannel arrays to produce droplets simultaneously from tens of thousands of microchannels at high production rates. The mechanisms of droplet generation in these microfluidic devices is known as the step microfluidic emulsification. The droplet size is independent on fluid flow rates in the dripping regime.

Collaborators: Prof Mitsutoshi Nakajima, Dr Isao Kobayashi, Dr Nauman Khalid

Reference

G.T.Vladisavljević, E.E. Ekanem, Z. Zhang, N. Khalid, I. Kobayashi, M. Nakajima, 2018. Chemical Engineering Journal, 333, 380-391.

SPG Membranes

SPG membranes are porous glass membranes with interconnected and tortuous pores widely used for membrane emulsification. We prepare emulsions with a narrow particle size distribution in the size range from less than 1 micron to more than 100 microns by either injecting a pure dispersed phase liquid through the membrane (filmed) or pushing a coarsely emulsified mixture of the dispersed and continuous phase through the membrane.

Reference

GT. Vladisavljević, I. Kobayashi, M. Nakajima, R.A. Williams, M. Shimizu and T. Nakashima, 2007, Journal of Membrane Science, 302, 243-253.

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